| Team name | Location | League | Level | Status |
|---|---|---|---|---|
| Chicago American Giants | Chicago, Illinois | Northern League | amateur | active |
| Chicago American Giants | Chicago, Illinois | Midwest Collegiate League | amateur | defunct |
| Chicago American Giants | Chicago, Illinois | Negro American League | professional | defunct |
| Chicago American Giants | Chicago, Illinois | Negro National League | professional | defunct |
| Cole's American Giants | Chicago, Illinois | Negro Southern League | professional | defunct |
| Cole's American Giants | Chicago, Illinois | professional | defunct | |
| Kansas City American Giants | Kansas City, Missouri | professional | defunct |